Los Cabos is located at the southern tip of Mexico's Baja California Peninsula, in the state of Baja California Sur. It encompasses the towns of Cabo San Lucas and San José del Cabo, as well as the Resort Corridor that lies between the two. The area's economy, like many resort areas in Mexico, was based on fishing but is now geared towards tourism, though sport fishing is one of the area's main attractions.

The municipality had a population of 164,162 inhabitants according to the 2005 census. It has an area of 3,451.51 km² (1,332.635 sq mi).